The epidemiology of avian influenza (AI) is complex. The AI virus constantly evolves by mutation and re-assortment with the emergence of new subtypes causing significant threat to both animal and human health. This report presents an overview of HPAI disease events (in poultry and non-poultry including wild birds) reported to the OIE by its Members in November 2019 through the World Animal Health Information System (WAHIS) early warning system. The stable situations reported through the six-monthly reports by 2 countries in the world namely Egypt and Indonesia are not described in this report as this data for the second semester 2019 will be collected in the beginning of 2020.