There are a number of commercial rapid immunochromatographic tests, also referred to as lateral flow devices (LFDs), for rabies virus (RABV) antigen detection available on the market. The test principle is based on immunoaffinity partition of the analyte between sample migrating laterally through a porous membrane and a finite “affinity zone” prepared by immobilizing an antibody on the membrane.
This document provides some recommendations on the use of commercial rapid immunochromatographic tests for rabies surveillance purposes.